However, the cats in group A had significantly higher T cell counts, CD4+ and CD8+ T lymphocyte counts, activated CD4+ T cell (CD4+CD25+) and B cell counts than the cats in group B at several time points throughout the study: T cells, CD4+ and CD8+ cells were higher in group A than in group B already within days after M. haemofelis exposure, while B cells were significantly higher in group A compared to group B later during the course of infection after maximal bacteremia (Figure 3A, B, C and E; all differences marked by asterisks). This evidence concerns the gene CD4 and infection.