KSHV-encoded latent nuclear antigen (LANA), Kaposin B, and K15 have been shown to regulate cells migration and invasion by modulating several cellular cancer-related miRNAs including the miR-221/miR-222 cluster and miR-31, which target ETS2 and ETS1, and the migration inhibitor FAT4, respectively [43,44]. This evidence concerns the gene ETS2 and cancer.