Previously, we analyzed BPH gene expression profile [23] and found that a gene encoding AKT interacting protein (NlAKTIP) in our Rh colony [reared on resistant Rathu Heenati (RHT, with Bph 3) rice stain] was downregulated 5-fold compared with that in our Tn colony (reared on susceptible Taichung Native 1 (TN1, with no resistance gene) rice stain). Here, AKTIP is linked to benign prostatic hyperplasia.