Studies in Caucasian and Asian populations have shown that polymorphisms in the genes IL-1B and IL-1RN were in conjunction with an increased risk for hypochlohydria and gastric carcinoma.13 According to our findings, individuals carrying the IL-1B-511*T/T allele compared to control group showed an increased OR for gastric cancer. The gene discussed is IL1B; the disease is gastric carcinoma.