Quantitative RT-PCR analysis for RNA isolated from PBMCs and adipose tissues revealed a 2.5 to 3.3-fold reduction in DNAJB3 expression in obese-T2D subjects, compared to obese non-diabetics, (P = 0.035 and 0.02 respectively, Fig. 1A). Here, DNAJB3 is linked to type 2 diabetes mellitus.