PTEN and neoplasm: Presence of the PTEN M264I mutation was analysed by direct sequencing method in TKI-refractory tumours other than liver metastases (metastases in left lung, peri-pancreatic lymph node, retroperitoneum lymph node 1, tumour embolism nodule in IVC, left adrenal grand, and left adrenal grand invading part to retroperitoneum); however, none harboured this mutation.