It found that significant differences exist in patients with hypertension history between the AA and AC + CC groups and between the three groups when doing an analysis on the genotype-phenotype of IL-23R rs10889677, which showed C allele may be a risk allele for gout patients to develop hypertension, however, it may need further research as C allele frequency of rs10889677 is smaller than A allele. This evidence concerns the gene IL23R and gout.