Specifically, highly sensitive sporadic PD lines showed a heightened toxicity to valinomycin treatment at doses of 20 μM (p < 0.001), 40 μM (p < 0.01), and 50 μM (p < 0.05) compared to healthy subject controls, which was equivalent to the mutant LRRK2 (G2019S) cell death profile (Supp. Here, LRRK2 is linked to Parkinson disease.