We identified three nonsynonymous variants that passed all filters, segregated with PD among the 5 individuals who underwent WES, and were confirmed by Sanger sequencing: USP1 c.573G > A (p.M191I), MVP c.2594G > T (p.G865V), and RAB39B c.574G > A (p.G192R) (Table 2). This evidence concerns the gene USP1 and Parkinson disease.