SDHA and osteosarcoma: We have previously found that the amount of mitochondrial translation products, the p.MT-CO1/succinate dehydrogenase complex subunit A (SDHA) ratio and the CIV/CS ratio were significantly lower after treatment with LIN in osteosarcoma 143B cybrids harboring the mtDNA m.3010A allele (Pacheu-Grau et al., 2013).