Mutations in three genes, including GJB2 (or CX26, Gene ID: 2706) [4], SLC26A4 (or PDS, Gene ID: 5172) [5] and the mitochondrial 12S rRNA gene (MTRNR1) [6], have been reported to be highly prevalent in SNHL patients across different populations. The gene discussed is GJB2; the disease is sensorineural hearing loss disorder.