Surprisingly, the HF patients with ischemic cardiomyopathy did not have significantly higher ANGPTL2 levels than those without ischemic cardiomyopathy (4.20 ng/mL (3.15–5.65 ng/mL) vs. 3.91 ng/mL (3.00–4.98 ng/mL], P = 0.13). Here, ANGPTL2 is linked to ischemic cardiomyopathy.