MTHFR and pyruvate carboxylase deficiency disease: The prevalence of anti-DFS70 antibodies (n = 7, 11.1%) in the 63 thrombophilic patients cohort was higher, although not statistically significantly, than the prevalence of factor V Leiden (9%, n = 6), G20210A polymorphism of prothrombin gene (8%, n = 5), AT and PS deficiencies (3%, n = 2 for each) and PC deficiency (n = 0) but lower than the prevalence of homozygote C677T polymorphism of MTHFR gene (13%, n = 9) and antiphospholipid antibodies (13.4%, n = 9).