In addition to the known fusion transcript for the 31 patients with CBF AML (CBFB-MYH11 and RUNX1-RUNX1T1), an additional 132 fusion transcripts (for 47 fusion events) were identified, including 21 inter- and 111 intra-chromosomal translocations. The gene discussed is RUNX1; the disease is acute myeloid leukemia.