The aim of the present substudy was therefore to investigate whether circulating levels of selected prothrombotic markers were associated with the degree of myocardial necrosis assessed by peak troponin T (TnT) and with left ventricular impairment assessed by left ventricular ejection fraction (LVEF) and N-terminal pro b-type natriuretic peptide (NT-proBNP) in STEMI patients. The gene discussed is NPPB; the disease is Myocardial necrosis.