In SLE patients who were in remission after treatment with corticosteroids and immunosuppressant, the expression levels of CCR4, CCR7, CCR8, CXCR1 and CX3CR1 on Vδ2 T cells were downregulated (Fig. 7A), and the percentage of peripheral Vδ2 T cells was increased but did not return to normal (Figs 1C and 7B). Here, CCR4 is linked to systemic lupus erythematosus.