Similar to the abnormal activation state of Vδ2 T cells in SLE patients, we found that antibody-induced T cell stimulation significantly upregulated the expression levels of CCR4, CCR7, CCR8, CXCR1 and CX3CR1 on Vδ2 T cells from HC. This evidence concerns the gene CX3CR1 and systemic lupus erythematosus.