IFNG and systemic lupus erythematosus: When we assessed the activation status of Vδ2 T cells, we found that most Vδ2 T cells secreted IFN-γ and TNF-α and that the Vδ2 T cell-mediated production of IFN-γ and TNF-α in SLE patients did not differ from that in HC (Fig. 2C).