In addition, the expression levels of CCR4, CCR7, CCR8, CXCR1 and CX3CR1 by Vδ2 T cells from SLE patients were significantly higher than those from HC (p < 0.05) (Fig. 5C,D), suggesting increased Vδ2 T cell trafficking to local tissues in SLE patients. Here, CCR8 is linked to systemic lupus erythematosus.