FAP and neoplasm: To determine whether the FAP-expressing tumor cell vaccine, which targets both CAFs and tumor cells, reverses the suppressive effects of tumors on the immune system by changing the immune cell milieu of the tumor microenvironment (TME), we performed flow cytometry to identify TAMs, MDSCs, Tregs and effector T cells (e.g., CD8+ CTLs) in the primary tumors.