Interestingly, expression of both miR-32 and -590-5p is increased in breast cancer samples compared with normal tissue (P=1.4e−31 for miR-32, P=6.18e−09 for miR-590-5p, Student's t-test; Supplementary Fig. 5e), and an inverse correlation is observed between BTG2 expression and miRNA-32 and -590-5p, supporting the relevance of these findings in clinical specimens (cor=−0.244, P=1.33e−11 for BTG2/miR-32; cor=−0.461, P=1.32e−40 for BTG2/miR-590-5p, Pearson's correlation; Supplementary Fig. 5f). Here, BTG2 is linked to breast cancer.