TNFRSF25 and B-cell chronic lymphocytic leukemia: Under basal conditions, CLL cells expressed low levels of DR3 when they were either freshly isolated (median RMFI = 1.00, range = 1.00–1.99 RMFI, n = 35; data not shown) or cultured in the absence of exogenous stimuli (Figures 1A–1C).