The χ2 test (Table 1) showed no significant statistical correlation of FAK or pFAK immunostaining with age, gender, tumor location, AJCC surgical stage, surgical type (amputation or limb salvage surgery) or histological response to pre-operative chemotherapy (tumor necrosis rate) (P < 0.05), suggesting that these variables are not associated with the expression of FAK and/or its phosphorylation status. Here, PTK2 is linked to neoplasm.