REL and Hodgkins lymphoma: Genome-wide association studies (GWAS) of HL have identified several common (minor allele frequency [MAF] >5%) single nucleotide polymorphisms (SNPs), at 2p16.1 (REL), 3p24.1 (EOMES), 6q23.3 (HBSL1L, MYB), 8q24.21 (PVT1), 10p14 (GATA3), 19p13.3 (TCF3), as well as multiple associations within 6p21 (HLA region)4, 5, 6, 7, 8, 9.