Cf had the opposite ratio and correspondingly high expression of Axis 5, and Mj had high expression of Axis 1 leading to gain of notable T cell signaling genes such as CD8, CCR5, IL2RA, and IL12RB. Mi had high Axis 2, which is enriched for erythropoiesis, and had high red blood cell counts, while Ml expressed four genes in directions expected of altered expression in leukemia (ENC1 up-regulated; FANCA, SIDT2, and SLC22A18 down-regulated). The gene discussed is IL2RA; the disease is leukemia.