In multivariable logistic regression analysis, after adjustment for age, severity of AS, BNP, left atrial size, E/e’, and LV mass, independent determinants of symptoms were sST2 (odds-ratio [OR] = 1.1, 95% confidence interval [CI] = 1.0–1.3; p = 0.037) and mitral E/e’ (OR = 1.35, CI = 1.02–1.8; p = 0.025). Here, NPPB is linked to aortic stenosis.