We found 11 of them to be up-regulated (IL10, IL15, IL2, LIF, FGF basic, IL4, GM-CSF, IFNγ, IL7, IL1RA and SCGFβ) while 2 to be down-regulated (IL12 (P40) and βNGF) in GBM tissue when compared to normal brain samples. The gene discussed is IL4; the disease is glioblastoma.