Recent evidence indicate that NAMPT may also have non-enzymatic functions as an inflammatory cytokine since its serum levels are increased in various inflammatory disorders [12], including sepsis [26], acute lung injury [27], rheumatoid arthritis (RA) [28], inflammatory bowel disease (IBD) [29], psoriasis [30] and myocardial infarction (MI) [31]. The gene discussed is NAMPT; the disease is rheumatoid arthritis.