In addition to MMP-9, there were three other factors independently associated with CHD incidence, namely: non-HDL cholesterol (HR per SD = 1.91 95% CI 1.41 to 3.04, p<0.001), smoking (HR = 2.71 95% CI 1.19 to 6.17, p = 0.017) and systolic blood pressure (HR per SD = 1.41 95% CI 1.17 to 1.96, p = 0.040). This evidence concerns the gene MMP9 and coronary artery disorder.