Genes PFDN4, CASP1, PLCE1, ICOSLG, GADD45G, SMARCA2, and TSPO are located in different chromosomes, and there are reports for changes in each one of these chromosomes in cervix cancer, for examples the reader is refer to: [10,61,76,77,78,79,80,81,82,83,84,85,86,87,88,89]. The gene discussed is ICOSLG; the disease is cervical cancer.