The analysis of the M1/M2 (NOS2/ARG1 and SOCS3/SOCS1) ratios (Figures 5E,F) expressed by A/J and B10.A cells demonstrates that curdlan increases but laminarin decreases the M1/M2 ratios of A/J macrophages induced by fungal infection. This evidence concerns the gene NOS2 and fungal infectious disease.