FUS mutations in patients with clinical FTLD are rare, and only four FUS mutations have so far been identified in patients with FTD-MND/ALS or in their families (Ticozzi et al., 2009; Blair et al., 2010; Broustal et al., 2010; Yan et al., 2010). The gene discussed is FUS; the disease is amyotrophic lateral sclerosis.