Annualized rates of whole brain atrophy, and consequently of ventricular expansion, are greatest in GRN, followed by sporadic FTD, C9ORF72, and lastly MAPT (Whitwell et al., 2015), in which similar rates of hippocampal atrophy have been observed (Whitwell et al., 2011b). Here, MAPT is linked to frontotemporal dementia.