KIAA0586 and Joubert syndrome: Most patients with KIAA0586-related JBTS exhibit few classical Hh phenotypes such as polydactyly (this study, Bachmann-Gagescu et al., 2015; Roosing et al., 2015), unlike the corresponding mouse, chicken, and zebrafish models (Davey et al., 2006; Bangs et al., 2011; Ben et al., 2011).