Most acute myeloid leukemia (AML) patients with adverse prognosis either fail to achieve complete remission (CR) or relapse after short-term remission, such as patients with complex karyotype, FLT3 mutiation, myelodysplasia-related changes, therapy-related AML (t-AML) [1], therapeutic options for these patients are limited. This evidence concerns the gene FLT3 and acute myeloid leukemia.