We demonstrated that BCL9 KD resulted in suppression of Wnt signaling as assessed by TOP-FLASH Wnt reporter assays in our basal DCIS cell line (DCIS.COM), while BCL9 KD in SUM225 (luminal HER2 overexpressing) did not affect the canonical Wnt signaling. This evidence concerns the gene BCL9 and ductal breast carcinoma in situ.