In humans, the situation is somewhat similar, in that our eQTL analysis of TCGA breast cancer cohort demonstrates that the expression level of NDN in primary tumors is associated with germline haplotypes in LD with NDN. However, closer scrutiny of this argument reveals another limitation of this study: although we identified NDN haplotypes as being associated with the expression levels of this gene, the same haplotypes were not associated with markers of clinical outcome in the TCGA cohort. The gene discussed is NDN; the disease is breast cancer.