IL12RB1 and myeloid sarcoma: Nevertheless, given that recombinant IL-12 p80 can also bind to IL-12Rβ1 [29], the common receptor subunit shared by the p40 cytokine family simultaneously targeting IL-12, IL-23, both monomer and homodimer of p40 might be more advantageous than antibodies against p40 subunit alone and provide more effective treatments for MS and EAE.