Xia et al. found that SOX9 is upregulated in pancreatic ductal adenocarcinoma (PDAC) and is associated with distant metastasis and unfavorable prognosis, and that upregulation of SOX9 is significantly relevant to tumor proliferation and could be a prognostic biomarker for PDAC [13]. Here, SOX9 is linked to pancreatic ductal adenocarcinoma.