Moreover, an inverse relationship has been documented between ARID1A and TP53 in uterine endometrioid [40, 41], gastric [29] and esophageal carcinomas [42], and between ARID1A and Phosphatase and TENsin homologue (PTEN) in colorectal and serous ovarian carcinomas [7]. This evidence concerns the gene PTEN and carcinoma of esophagus.