Considering adjusted HRs instead of number of cancer recurrences, studies of urological cancers (HR = 2.25, 95%CI: 1.60–3.15, p < 0.0001, I2 = 78%) and those conducted in Asia (HR = 2.37, 95%CI: 1.54–3.66, p < 0.0001, I2 = 88%) significantly moderated the association between loss of ARID1A and risk of cancer recurrence adjusting survival analyses for potential confounders (Supplementary Table 5). This evidence concerns the gene ARID1A and cancer.