INS and cardiovascular disorder: Another recent study [19] demonstrated that NC was positively associated with cardiovascular disease risk factors such as SBP, insulin, and homeostatic model assessment of insulin resistance, and was negatively associated with the quantitative insulin sensitivity check index, fasting glucose to insulin ratio, and serum levels of high-density lipoprotein cholesterol both in bivariate and multivariate analyses conducted in Greek children of both sexes aged 9–13 years.