Further analyses with ANOVA showed that baseline levels of YKL-40 were higher in MCI patients who progressed to AD (n = 36) compared with stable MCI patients (n = 17, mean (SE), 327 (19) ng/ml vs. 242 (31) ng/ml, p = 0.01), as shown in Table 3. Here, CHI3L1 is linked to Alzheimer disease.