In addition, results were virtually identical when analyzing for progression of MCI to all types of dementia (n = 44) instead of progression to AD alone (HR (95 % CI): YKL-40 3.2 (1.3–7.9) for the highest tertile and 2.9 (1.1–7.2) for the middle tertile; VILIP-1 3.8 (1.5–9.4) for the highest tertile and 1.7 (0.6–4.4) for the middle tertile). Here, CHI3L1 is linked to dementia.