Specifically, 1) a polymorphism of Gabbra2 is associated with mTLE34; 2) GalR1 deletion exacerbates hippocampal neuronal loss after kainate administration in mice35, and GalR1 knockout mice exhibit spontaneous epilepsy, abnormal EEGs, and altered inhibition in the hippocampus36; 3) Gria2 in the hippocampus is related to the mechanisms of seizure and neurodegeneration37. Here, GALR1 is linked to epilepsy.