Similarly, considering viral genotype and the response to IFN‐based therapy, IFN‐λ3/4 and centromeric A KIR haplotypes are important for treatment‐induced resolution of patients infected with HCV G1, whereas the KIR2DL3 and HLA‐class I combination, but not IFN‐λ3/4, plays a dominant role in resolving HCV G2 and G3 infection. This evidence concerns the gene KIR2DL3 and infection.