In order to investigate whether similar polymorphisms were associated with disease progression, we analyzed the frequency of IFN‐λ3/4 rs12979860 CC, TapG:HLA‐B114D, KIR and HLA polymorphisms known to be important for HCV resolution in patients with chronic hepatitis C who developed cirrhosis compared with those who did not. Here, IFNL3 is linked to chronic hepatitis C virus infection.