PGR and basal cell carcinoma: For example in MRC-5 fibroblasts, genes PGR and ADH1B belonging to pathways “Oocyte meiosis” and “Propanoate metabolism” were the only genes which were up-regulated and Wnt16 belonging to “Basal cell carcinoma” pathway was the only gene which was down-regulated with a log2 fold change >1.