CRP and Familial prostate cancer: Several studies on the association between levels of the inflammatory marker CRP and risk of prostate cancer have reported negative results however these studies used small sample sizes in case-controlled study designs (Platz et al., 2004; Siemes et al., 2006; De Marzo et al., 2007; Allin et al., 2009; Heikkilä et al., 2011).