It is also interesting that one of the two other medulloblastoma cell lines tested (UW-228-2) had an only minimal band reactive with the BRCA2 antibody on western blotting (Figure S1 in Supplementary Material), suggesting that BRCA2 needs to be examined in more detail in additional samples of medulloblastoma, especially when associated with inactivation of TP53 (49, 51). This evidence concerns the gene TP53 and medulloblastoma.