Yurkovetsky et al, reported a higher level of IL-1α, IL-1β, IL-6, IL-8, IL-12p40,IL-13, GM-CSF, MCP-1, MIP-1α, MIP-1β, IFN-α, TNF-α, EGF, VEGF, and TNF-RII in the plasma of melanoma patients compared with healthy controls [12]. Here, TNF is linked to melanoma.