We determined the plasma concentrations of L59 LAP-DPs in carbon tetrachloride (CCl4)-treated mice (Fig. 4a, closed columns) and compared them with corresponding hepatic hydroxyproline (HDP) content, which reflects the amount of accumulated collagen or the extent of liver fibrosis (Fig. 4a, open columns). Here, TGFB1 is linked to Hepatic fibrosis.