It has been shown that DC-SIGN recognizes carcinoembryonic antigen (CEA), a well-known tumor-associated antigen overexpressed on almost all human colorectal, gastric, and pancreatic adenocarcinomas, 70% of non-small cell lung carcinomas, and 50% of breast carcinomas A (50). This evidence concerns the gene CEACAM5 and pancreatic adenocarcinoma.