Many of the anti-inflammatory genes in Table 3 are not directly associated with PAD or CAD based on PubMed search, such as ADORA2B (adenosine A2b receptor), EDNRA (endothelin receptor type A), FCER1G (Fc receptor, IgE, high affinity I, gamma polypeptide), STAT5B (signal transducer and activator of transcription 5B), and TLR9 (toll-like receptor 9). This evidence concerns the gene ADORA2B and coronary artery disorder.