This result agrees with previous reports showing reduced expression of genes related to glutamatergic (Arc, Gria1, Gria2, Grik4, Psd95), or GABAergic (Gad67, Gabarap-11) neurotransmission and vesicle trafficking (Syn3, Syb, Synj, Snap29, Syp, Stx4a, Stx7) in hTau mice (Alldred et al., 2012), and elevation of inflammatory genes in brain regions containing amyloid deposits in APP mice (Dickey et al., 2003; Landel et al., 2014). The gene discussed is APP; the disease is amyloidosis.