NOS2 and infection: To determine whether lung epithelial cells produce iNOS during pulmonary F. tularensis LVS infection in vivo, we harvested lungs from mice 7 days after sublethal LVS intranasal infection, and examined co-localization of iNOS with pro-Surfactant Protein-C (pro-SP-C), a protein shown to be specifically produced by ATII cells [17].