NRON and hepatocellular carcinoma: This is consistent with our discrepant observations that repressed Kcnq1ot1 and NRON were observed in HBV-related HCC tumor compared with adjacent non-tumor tissues (Table 3), while up-regulated Kcnq1ot1 and NRON were found in HBV-related HCC compared with viral negative non-tumor tissues (Table 4).